1- Anti-inflammation

Piperine can inhibit production of pro-inflammatory cytokines. Thereby, it cuts down expression of

inflammatory cytokines such as interleukin 1, interleukin 6, tumor necrosis factor α, etc. Therefore,

Piperine can reduce inflammation and pain. It exerts an banti-inflammatory effect.

2-Promotion of penetration

Piperine can be absorbed through skin, and act directly on subcutaneous tissues, nerves and blood vessels.

Thus Piperine can significantly improve and promote absorption and utilization of active ingredients in skin.

Also it can help cosmetic ingredients quickly penetrate into skin.

3-Anti-oxidation

Piperine can reduce oxidative stress damage of cells in the process of oxygen free radicals generation and

scavenging. Additionally, it has certain scavenging capacity to hydroxyl and DPPH free radicals. It exhibits

anti-oxidation property. Its anti-oxidative capacity is equivalent to 60.05% of vitamin C; and it is stable in acidic medium.

4-Other function

Piperine can stimulate activity of melanocytes. It increases the amount of tyrosine, and promotes expression of

TPR1. Thus Piperine accelerates synthesis of melanin in epidermal melanocytes. It can be added into cosmeceuticals

for treatment of depigmentation dermatosis.

Application:
Piperine is mainly used in cosmetics. It can be used as an osmotic agent to add into toner, emulsion, facial cream,

essence and other skin care products. It can also acts as fragrance of perfume. Moreover, Piperine is an active ingredient

in cosmetics to treat depigmentation dermatosis.

Why do we use Supercritical CO2 Fluid Extraction?

1-The operation is close to room temperature (34 ~ 39 °C) , and the whole extraction process is covered with CO2 gas,

which effectively prevents the oxidation and degradation of heat-sensitive materials. It can completely retain the biological

activity, and can extract the substance with high boiling point, low volatility and pyrolytic at the temperature far below its boiling point.

2- Supercritical co2 Fluid Extraction is the most environmentally friendly extraction method, the whole process does not contain

organic solvents, so the extract without residual solvents, thus preventing the extraction process of human harmful substances and

pollution of the environment, to ensure 100% of the natural.

3-Supercritical co2 Fluid Extraction also has the function of anti-oxidation and sterilization, which is beneficial to guarantee and improve the quality of products.